Expression of H_v1 Proton Channels in Myeloid-Derived Suppressor Cells (MDSC) and Its Potential Role in T Cell Regulation

Researchers demonstrated that mouse MDSCs expressed functional Hv1 proton channels by immunofluorescence microscopy, flow cytometry, and Western blot, besides performing a biophysical characterization of its macroscopic currents via patch-clamp technique.