The Double Agents in Liquid Biopsy: Promoter and Informant Biomarkers of Early Metastases in Breast Cancer

Investigators discuss in detail the divergence of early metastases as circulating tumor cells (CTCs) and the involvement of microRNAs (miRNAs) as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer, serial monitoring of therapeutic response, and the dynamic molecular adaptations induced by miRNAs on CTCs.