Lon Upregulation Contributes to Cisplatin Resistance by Triggering NCLX-Mediated Mitochondrial Ca2+ Release in Cancer Cells

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Scientists reported the role of Lon in the response to cisplatin-induced mtDNA damage and oxidative stress, which conferred cancer cells on cisplatin resistance via modulating calcium levels in mitochondria and cytosol.
[Cell Death & Disease]

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