KLF5 Inhibition Overcomes Oxaliplatin Resistance in Patient-Derived Colorectal Cancer Organoids by Restoring Apoptotic Response

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Researchers constructed colorectal cancer PDOs and selected the Kruppel-like factor 5 (KLF5) inhibitor ML264 as the research object based on the results of an in vitro drug screening assay.
[Cell Death & Disease]

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