All Articles by Author:

Britya Ghosh

Predictors of Kidney Complications and Analysis of Hypertension in Children with Allogeneic Hematopoietic Stem Cell Transplantation

[Pediatric Nephrology] Researchers determined incidence of kidney complications in pediatric allogeneic hematopoietic stem cell transplantation patients.

Emerging Antibody-Based Therapies for the Treatment of Acute Myeloid Leukemia

[Cancer Treatment Reviews] Scientists discuss current concepts of antibody-based therapies and results from emerging antibody-based therapeutics for the treatment of acute myeloid leukemia.

Adial Pharmaceuticals Announces Research Collaboration with the Medical College of Wisconsin to Advance Purnovate’s Adenosine Compounds as Potential Treatments for Diabetes and NASH

[ADial Pharmaceuticals Inc.] Adial Pharmaceuticals, Inc. announced that Purnovate, Inc. has entered into a research collaboration with the Medical College of Wisconsin, a leading medical school, and Dr. John Auchampach, PhD, Professor and Vice Chair of the Department of Pharmacology and Toxicology.

Chronic Effects of Two Rutile TiO2 Nanomaterials in Human Intestinal and Hepatic Cell Lines

[Particle and Fibre Toxicology] Scientists investigated the cytotoxic effects of repeated exposure of relevant models of intestine and liver to two TiO2 nanomaterials differing in hydrophobicity for 24 hours, 1 week and 2 weeks at concentrations ranging from 0.3 to 80 µg/cm2.

Macrophages Evoke Autophagy of Hepatic Stellate Cells to Promote Liver Fibrosis in NAFLD Mice via the PGE2/EP4 Pathway

[Cellular and Molecular Life Sciences] Scientists found that liver macrophages were polarized toward type 2 during the progression of nonalcoholic steatohepatitis (NASH) and liver fibrosis in both patients and NAFLD mice.

Roles of DKK3 in Cellular Adhesion, Motility, and Invasion through Extracellular Interaction with TGFBI

[FEBS Journal] Researchers focused on the extracellular function of Dickkopf-related protein (DKK) 3 as a secreted protein, and identified Transforming Growth Factor Beta Induced protein ig-h3 (TGFBI) as a secreted protein interacting with DKK3.

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CAR Affinity Modulates the Sensitivity of CAR-T Cells to PD-1/PD-L1-Mediated Inhibition

[Nature Communications] The authors interrogated CAR-T cells targeting HER2 with either low or high affinity in various preclinical models.

Emx2 Underlies the Development and Evolution of Marsupial Gliding Membranes

[Nature] By combining epigenomics, transcriptomics and in-pouch marsupial transgenics, scientists showed that Emx2 was a critical upstream regulator of patagium development.

Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Load-Bearing Capacity

[Tissue Engineering Part A] Cmputational simulations revealed that interfacial fibrils within a bilayer alter osteochondral scaffold deformation patterns by redirecting load-induced stresses toward the top of the cartilage layer.