Ishira

[Clinical Immunology] The authors investigated the involvement of sublytic C5b-9 effector Response Gene to Complement 32 (RGC-32) in cell cycle activation, phenotypic switch, and production of extracellular matrix in smooth muscle cells.

[Kaohsiung Journal of Medical Sciences] Scientists examined the underlying mechanisms of microRNA-708-5p (miR-708-5p)/sodium-phosphate transporter 1 (Pit-1) axis in high phosphate-induced vascular calcification of T/G HA-vascular smooth muscle cells.

[Skeletal Muscle] The authors discuss the diverse ways by which Notch signaling factors and other modifying partners are operating during the lifetime of muscle stem cells to establish an adaptive dynamic network.

[BioAge Labs, Inc. (Businesswire, Inc.)] BioAge Labs, Inc. announced that the first cohort has been dosed in a Phase Ib trial of BGE-105, a highly selective and potent small-molecule agonist of the apelin receptor APJ, which regulates multiple aspects of muscle metabolism, growth, and repair.

[Scientific Reports] Investigators showed that interferon-γ treatment induced expression of major histocompatibility class-I genes and PD-L1 in prostate cancer cells in vitro.

[Nature Reviews Urology] Understanding precision medicine, personalized cancer risk management and syndrome-related cancer risk management is important in order to develop collaborative strategies with genetic counselling for optimal care of patients and their families