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Extracellular Matrix News is an online resource that keeps scientists updated on the latest extracellular matrix research.
Cardiovascular Magnetic Resonance Radiomics to Identify Components of the Extracellular Matrix in Dilated Cardiomyopathy
[Circulation] Researchers investigated whether cardiovascular magnetic resonance radiomics analysis can distinguish between noncollagen and inflammation from collagen in dilated cardiomyopathy.
Current Understanding of the Interplay Between Extracellular Matrix Remodelling and Gut Permeability in Health and Disease
[Cell Death Discovery] The authors bring together the current knowledge of the interplay between gut barrier, immune and ECM features in health and disease, discussing the role of barrier permeability as a discriminant between homoeostasis and Inflammatory Bowel Disease.
Immunohistochemical Properties of Embryonic Telocytes in a Myogenic Microenvironment
[Scientific Reports] Researchers investigated the immunohistochemical features of embryonic telocytes during myogenesis and describe their morphology using light microscopy and TEM.
3D Printed Multifunctional Biomimetic Bone Scaffold Combined with TP-Mg Nanoparticles for the Infectious Bone Defects Repair
[Small] Scaffolds mimicked the structure and components of cancellous bone with high mechanical strength based on α-TCP self-curing properties through low-temperature 3D printing.
Lgr6-Expressing Functional Nail Stem-Like Cells Differentiated From Human-Induced Pluripotent Stem Cells
[PLOS One] Investigators achieved the successful differentiation of nail stem-like cells from human-iPSCs via digit organoids by stepwise stimulation, tracing the molecular processes involved in limb development.
Enhancing Cellular Behavior in Repaired Tissue via Silk Fibroin-Integrated Triboelectric Nanogenerators
[Microsystems & Nanoengineering] Scientists presented a flexible silk fibroin-based triboelectric nanogenerator that featured an on-skin substrate and is characterized by excellent skin compliance and air/water permeability.
Transdifferentiation of Fibroblasts Into Muscle Cells to Constitute Cultured Meat with Tunable Intramuscular Fat Deposition
[eLife] Researchers employed the myogenic/lipogenic transdifferentiation of chicken fibroblasts in 3D to produce muscle mass and deposit fat into the same cells without the co-culture or mixture of different cells or fat substances.
Establishment of Homotrimer Collagen Type I Signature and Its Association with Clinical Manifestation and Tertiary Lymphoid Structures Formation in Liver Cancer
[Heliyon] Using transcriptional and immunoflourance method, investigators established homocol signautre, which was able to transcriptionally and histologically detect homotrimeric collagen type I.
Development of an Alginate–Chitosan Biopolymer Composite With dECM Bioink Additive for Organ-on-a-Chip Articular Cartilage
[Scientific Reports] Investigators proposed a novel approach for using a combination of biopolymers and decellularised EC ECM as a bioink additive in the development of scalable organs-on-a-chip using a microfluidic platform.
Gut Microbial Metabolite Targets HDAC3-FOXK1-Interferon Axis in Fibroblast-Like Synoviocytes to Ameliorate Rheumatoid Arthritis
[Bone Research] Researchers showed that transplantation of fecal microbiota of collagen-induced arthritis (CIA)-resistant C57BL/6J mice to CIA-susceptible DBA/1J mice confer CIA resistance in DBA/1J mice. C57BL/6J mice and healthy human individuals have enriched B. fragilis than DBA/1J mice and rheumatoid arthritis patients.
DNA Nanoparticle Based 2D Biointerface to Study the Effect of Dynamic RGD Presentation on Stem Cell Adhesion and Migration
[Small] In this approach, mesoporous silica nanoparticles were functionalized with single-strand DNA and spin-coated on a glass substrate to create the 2D bio interface.
The β-arrestin1/Endothelin Axis Bolsters Ovarian Fibroblast-Dependent Invadosome Activity and Cancer Cell Metastatic Potential
[Cell Death & Disease] The authors identified ET-1 as a pivotal factor in the activation of cancer-associated fibroblasts capable of proteolytic ECM remodeling and the generation of heterotypic spheroids containing cancer cells with a propensity to metastasize.
The Extracellular Matrix News team is proud to provide an essential resource on the latest publications, reviews, industry news, and jobs relevant to the matrix research community. Topics include extracellular matrix-cell interactions, extracellular matrix protein characterization and their application in tissue engineering and regenerative medicine, and the development and characterization of synthetic scaffolds.
