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Pulmonary Cell NewsTreatment of glioma cells with the dopamine receptor antagonist quetiapine reduced glioma cell self-renewal in vitro and combined treatment of mice with quetiapine and radiation prolonged the survival of glioma-bearing mice.
[JNCI-Journal of the National Cancer institute]
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Bhat, K., Saki, M., Cheng, F., He, L., Zhang, L., Ioannidis, A., Nathanson, D., Tsang, J., Bensinger, S. J., Nghiemphu, P. L., Cloughesy, T. F., Liau, L. M., Kornblum, H. I., & Pajonk, F. (2021). Dopamine Receptor Antagonists, Radiation, and Cholesterol Biosynthesis in Mouse Models of Glioblastoma. JNCI: Journal of the National Cancer Institute, djab018. https://doi.org/10.1093/jnci/djab018 Cite
