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Pulmonary Cell NewsResearchers investigated whether and how cancer-associated fibroblasts (CAFs) regulated myeloid-derived suppressor cells function to enhance cancer stemness, the driving force of the cancer aggressiveness and chemotherapy refractoriness, in highly desmoplastic intrahepatic cholangiocarcinoma.
[Hepatology]
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Lin, Y., Cai, Q., Chen, Y., Shi, T., Liu, W., Mao, L., Deng, B., Ying, Z., Gao, Y., Luo, H., Yang, X., Huang, X., Shi, Y., & He, R. (n.d.). CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5-lipoxygenase. Hepatology, n/a(n/a). https://doi.org/10.1002/hep.32099 Cite
