CITED2 Coordinates Key Hematopoietic Regulatory Pathways to Maintain the HSC Pool in Both Steady-State Hematopoiesis and Transplantation

While hematopoietic-specific Cited2 deletion has a minor impact on steady-state hematopoiesis, Cited2-deficient hematopoietic stem cells are severely depleted in young mice and fail to expand upon aging.