Hypoxia Preconditioned Mesenchymal Stem Cell-Derived Exosomes Induce Ex Vivo Expansion of Umbilical Cord Blood Hematopoietic Stem Cells CD133⁺ by Stimulation of Notch Signalling Pathway

Scientists examined the importance of hypoxia-preconditioned mesenchymal stem cells-derived exosomes and normoxia-preconditioned MSC-derived exosomes in the self-renewal and long-term clonogenic potential of umbilical cord blood hematopoietic stem cells.