Scientists explored the mechanism of fluoride interference in the immune system and also identify the key indicators of fluoride-induced immune damage. [Human Reproduction] AbstractGraphical Abstract

Researchers investigated whether and how bevacizumab regulated ferroptosis and immune activity in liver cancer. They performed RNA-sequencing in bevacizumab-treated human liver cancer cell line...

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Scientists deciphered a mechanism that enabled the proliferation and differentiation of satellite cells through the downregulation of trans-2,3-enoyl-CoA reductase like (TECRL) during muscle regeneration.

[Stem Cell Research & Therapy] The authors provide a brief overview of erythropoiesis and examine endeavors to recapitulate erythropoiesis in vitro using various cell sources.

[Journal of Translational Medicine] The authors evaluated the feasibility of intraperitoneal administration of non-virally engineered MSCs to co-deliver cytosine deaminase and uracil phosphoribosyl transferase/5-Flucytosine prodrug system and interferon-beta to potentially enhance the cGAS-STING signaling axis.

[Development] Investigators showed that, in contrast to prior reports, bone morphogenic protein signaling (SMAD1/5/9 phosphorylation) is not detectable until implantation when it is detected in the primitive endoderm – an extraembryonic lineage.

[Journal of Genetics and Genomics] Scientists showed that GPR160, a class A member of G protein-coupled receptors, was dramatically downregulated concurrent with mESC differentiation into embryoid bodies in vitro.

[Molecular Cancer Research] Investigators described small-cell lung cancer cell lines harboring amplification of MYC and MYCN, but not MYCL1 nor non-amplified MYC cell lines, exhibited superior sensitivity to treatment with the pan-BET bromodomain protein inhibitor Mivebresib.

[Molecular Cancer Research] Pulmonary fibrosis was induced in BALB/c mice by oropharyngeal aspiration of a single dose of bleomycin

[Molecular Biology Reports] The authors collected a large amount of evidence on the anti-prostate cancer effects of these six flavonoids, including a large number of cellular experiments and a small number of preclinical animal experiments.

[Weill Cornell Medicine (EurekAlert)] A team led by Dr. Eddie Imada has been awarded a three-year, $1.5 million United States Department of Defense grant for research on a cellular process called alternative polyadenylation and its role in prostate cancer.

Researchers explored whether licochalcone D could regulate lipid accumulation in fatty liver cells. FL83B hepatocytes were incubated with oleic acid to establish a fatty...