Tag results:
AKT
Pancreatic Cell News
The Parasite-Derived Peptide FhHDM-1 Activates the PI3K/Akt Pathway to Prevent Cytokine-Induced Apoptosis of β-Cells
[Journal of Molecular Medicine] Scientists showed that proteomic analyses of pancreas tissue from non-obese diabetic (NOD) mice suggested that FhHDM-1 activated the PI3K/Akt signalling pathway, which was associated with β-cell metabolism, survival and proliferation.
Dermal Cell News
Non-thermal Atmospheric Pressure Plasma Activates Wnt/β-Catenin Signaling in Dermal Papilla Cells
[Scientific Reports] The human dermal papilla (DP) cells, isolated fresh hair follicles, and mouse back skin were exposed with the non-thermal atmospheric pressure plasma.
Dermal Cell News
Non-Thermal Atmospheric Pressure Plasma Activates Wnt/β-Catenin Signaling in Dermal Papilla Cells
[Scientific Reports] Human dermal papilla cells, isolated fresh hair follicles, and mouse back skin were exposed with the non-thermal atmospheric pressure plasma. Biological outcomes were measured using RNA-sequencing, RT-PCR, Western blots, and immunostaining.
Intestinal Cell News
ITLN1 Inhibits Tumor Neovascularization and Myeloid Derived Suppressor Cells Accumulation in Colorectal Carcinoma
[Oncogene] Researchers explored the inhibitory role of ITLN1 in the tumor-permissive microenvironment that existed during the first occurrence and subsequent development of colorectal carcinoma.
Mammary Cell News
Adaptor SH3BGRL Promotes Breast Cancer Metastasis through PFN1 Degradation by Translational STUB1 Upregulation
[Oncogene] The authors reported that a small adaptor protein, SH3BGRL, was upregulated in the majority of breast cancer patients, especially elevated in those with metastatic relapse, indicating it as a marker for the poor prognosis of breast cancer.
Mammary Cell News
Targeting Gi/O Protein-Coupled Receptor Signaling Blocks HER2-Induced Breast Cancer Development and Enhances HER2-Targeted Therapy
[JCI Insight] In mammary epithelial cells of transgenic mouse models, and breast cancer cell lines, HER2 hyperactivation altered GPCR expression, particularly, Gi/o-GPCRs.