CD31

[Scientific Reports] Reserachers investigated the effects of hyperbaric oxygen treatment (HBOT) on solid tumors, such as lung cancer. Non-small cell human lung carcinoma A549-cell-transferred severe combined immunodeficiency mice were selected as an in vivo model to detect the potential mechanism of HBOT in lung tumors.

[Stem Cells and Development] Investigators aimed to fabricate a Matrigel scaffold loaded with human umbilical cord-derived MSCs and explore its potential to restore ovarian function and repair ovarian structures in vitro and in vivo.

[Cancer Gene Therapy] Angiogenesis was evaluated in the Matrigel-based human umbilical vein endothelial cell-RLC-310 coculture model and immunohistochemical staining for vascular endothelial growth factor and CD31 in tumor tissues collected from a xenograft ccRCC mouse model.

[Cell Death & Disease] Scientists found a decrease in endothelial cells and an increase in cells co-expressing CD31 and α-smooth muscle actin at eight weeks in heart tissue of mice subjected to transverse aortic constriction, which implied EndMT.

[Journal of Dental Research] Vascularized dental pulp stem cells (DPSC) constructs were fabricated by inducing endothelial differentiation, and then scientist investigated the behavior of differentiated DPSCs, the internal structure of cell constructs, and their pulp regenerative ability in vivo.

[Experimental Cell Research] To help identify new strategies for antiangiogenic therapy in gastric cancer (GC), scientists evaluated miR-205-5p expression in GC tissues from TCGA database and our hospital, and its functions in angiogenesis were explored in vitro and in vivo.