[Cell Death & Disease] The authors found that ectopic restoration of DNAJB9, a member of the heat shock protein 40 family, inhibited the migration, invasion, in vivo metastasis, and lung colonization of TNBC cells by inhibiting the epithelial–mesenchymal transition and metastasis.
[Nature Communications] Scientists provided evidence that the Activating Molecule in Beclin-1-Regulated Autophagy (Ambra1) contributed to melanoma development.
[Molecular Oncology] Mechanistic studies revealed that Tspan5 promoted cell migration and tumour metastasis by increasing the enzymatic maturation of ADAM10 and activating Notch signalling via the increase of the cleavage of the Notch1 receptor catalysed by the γ‐secretase complex.
[Oncology Reports] established cancer stem‑like cells derived from large‑cell lung cancer cells, NCI‑H460 and H661, and revealed that Schisandrin B inhibited the viability of cancer stem‑like cells at concentrations of ≥40 µmol/l.