HIV

[PLoS Neglected Tropical Diseases] Scientists investigated the expression of FOXP3+ Treg cells in leprosy skin lesions and to correlate their clinical forms, laboratory characteristics, and the immune reconstitution syndrome in HIV-leprosy co-infection.

[ScienceInsider] Opening a new chapter in the treatment of COVID-19—one borrowed from successfully tackling the AIDS virus—the drug behemoth Pfizer reported upbeat results for a 5-day pill regimen to treat early infections with SARS-CoV-2.

[ACS Chemical Neuroscience] Investigators synthesized biodegradable polymeric nanoparticles loaded with darunavir and luminescent, nontoxic carbon dots, and investigated their ability to permeate through an artificial blood–brain barrier and to inhibit in vitro matrix metalloproteinase-9.

[Gilead Sciences, Inc.] Gilead Sciences, Inc. announced the FDA approved a new low-dose tablet dosage form of Biktarvy® for pediatric patients weighing at least 14 kg to less than 25 kg who are virologically suppressed or new to antiretroviral therapy.

[Science Advances] Scientists showed that HIV-1 proviruses integrated in the first introns of signal transducer and activator of transcription 3 and lymphocyte-specific protein tyrosine kinase could play an important role in the development of T cell lymphomas.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists examined the tRNA and mRNA pools of T cells during their vigorous proliferation and differentiation upon triggering their antigen receptor.