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IL-6

Histone Deacetylase Inhibitors Attenuated Interleukin-1β-Induced Chondrogenesis Inhibition in Synovium-Derived Mesenchymal Stem Cells of the Temporomandibular Joint

[Bone & Joint Journal] Synovium-derived MSCs (SMSCs) were isolated from synovium specimens of patients undergoing temporomandibular joint surgery. Chondrogenic differentiation potential of SMSCs was evaluated in vitro in the control, IL-1β stimulation, and IL-1β stimulation with histone deacetylase inhibitors groups.

A Comparative Study on the Model of PM2.5 Direct or Indirect Interaction with Bronchial Epithelial Cells

[Environmental Science and Pollution Research] The authors examined the viability of BEAS-2B and mRNA/protein expression profile of oxidative stress and inflammatory response-related transcription factors Nrf2, NF-kB, and according inflammatory indicators such as IL-1, IL-6, and IL-8, with a view to evaluating the effects of different interaction models of PM2.5 on epithelial cell damage in vitro.

NiONPs-Induced Alteration in Calcium Signaling and Mitochondrial Function in Pulmonary Artery Endothelial Cells Involves Oxidative Stress and TRPV4 Channels Disruption

[Nanotoxicology] In this in vitro study scientists assessed the cytotoxic effects of nickel oxide nanoparticles (NiONPs) on human pulmonary artery endothelial cells.

Effects of Acanthus ebracteatus Vahl. Extract and Verbascoside on Human Dermal Papilla and Murine Macrophage

[Scientific Reports] In controlled in vitro assays it was found that Acanthus ebracteatus Vahl. extract and verbascoside at various concentrations induced dermal papilla cell proliferation which was indicated by an increase in the number of cells in the S and G2/M phases of the cell cycle.

The Effects of Citrus Flavonoids and Their Metabolites on Immune-Mediated Intestinal Barrier Disruption Using an In Vitro Co-Culture Model

[British Journal of Nutrition] Researchers assessed the effect of citrus flavonoids and their intestinal metabolites on immune-mediated barrier disruption in an in vitro co-culture model.

NLRP3 Inflammasome Activation in Human Peripheral Blood Mononuclear Cells Induced by Venoms Secreted PLAM2s

[International Journal of Biological Macromolecules] Peripheral blood mononuclear cells were isolated by density gradient and incubated with RPMI, LPS, BthTX-I or BthTX-II isolated from Bothrops jararacussu venom, to evaluate viability, and the results showed that there was no cell death.

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