MTOR

[Cell Death & Disease] ADRB3 promoted metastasis by inducing mobilization and inhibiting differentiation of both breast cancer cells and myeloid-derived suppressor cells.

[Angiogenesis] Scientists dissected vascular cues influencing glioblastoma stem cells (GSCs) gene expression and function to perfusion-based vascular cues, as well as to those requiring direct GSC-endothelial cell contacts.

[Brain] To model human malformations of cortical development associated with nitrogen permease regulator-like 3 (NPRL3) variants, researchers created a focal Nprl3 KO in fetal mouse cortex by in utero electroporation and found altered cortical lamination and white matter heterotopic neurons

[Cell Death & Disease] The authors investigated the biological functions and potential molecular mechanisms of miR-7-5p in NSCLC undergoing treatment with Everolimus.

[iScience] The authors found that Reh acute lymphoblastic leukemia cells bearing the KRAS-G12D mutation showed increased proliferation rates in vitro but displayed severely compromised growth in mice.

[Science Advances] eEF-2K KO CD8+ T cells were more metabolically active and showed hyperactivation of the Akt-mTOR-S6K pathway.