PBMCs

[Cellular & Molecular Immunology] Scientists summarize the recent advances in expansion strategies with or without genetic manipulation of NK cells derived from various cellular sources.

[Vaccine] Investigators identified immunodominant portions of four malaria vaccine candidate antigens using peripheral blood mononuclear cells from adults with life-long exposure to malaria parasites.

[Clinical Cancer Research] Investigators examined the role of the CD137+ T cells in the improvement of patients' selection for immunotherapy treatment.

[Proteome Science] Human peripheral blood mononuclear cells were stimulated with macrophage colony-stimulating factor, and obtained macrophages were transformed into foam cells by oxidized low-density lipoprotein.

[Redox Biology] Researchers reported that β-glucan-trained macrophages from mice harboring a myeloid-specific deletion of the catalytic subunit of glutamate-cysteine ligase showed impaired GSH synthesis and decreased proinflammatory cytokine production in response to lipopolysaccharide challenge.

[Communications Biology] Researchers showed that in mice early-stage CD71+ erythroid cells expanded in anemia, had high levels of arginase 2 and reactive oxygen species.