[Clinical and Translational Medicine] Investigators explored the impacts of prostate cancer-associated ncRNA transcripts 1 (PCAT1) on tumorigenesis and radioimmune responses and the underlying molecular mechanisms in NSCLC.
[Anti-Cancer Drugs] Scientists investigate the effect of Ubiquitin-specific protease 1 (USP1) depletion with chemotherapeutant doxorubicin on the hepatocellular carcinoma cells.
[British Journal of Cancer] Scientists demonstrated that lysine acetyltransferase 6 A (KAT6A) expression was upregulated in HCC tissues and cell lines. Clinical analysis showed that increased KAT6A was significantly associated with malignant prognostic features and shorter survival.
[Cell Death & Disease] Scientists showed that the expression of UPF1 was upregulated in endometrial cancer tissues and endometrial cancer stem cells and correlated with poor clinicopathological characteristics.
[Cell Death Discovery] Researchers performed GEO dataset analysis and identified that claudin1 was a critical regulator of epidermal growth factor receptor tyrosine kinase inhibitors resistance in NSCLC cells.