Sox2

[Stem Cells and Development] Compared with tumor-adjacent normal tissues, death-associated protein kinase 1 (DAPK1) expression was reduced in prostate cancer cell lines with respect to that in normal prostate cells.

[Development] Investigators reported that the conjunct activity of two orphan nuclear receptors, Esrrb and Nr5a2, paralleled the importance of that of Oct4 and Sox2 in naïve ESCs.

[Journal of Cellular and Molecular Medicine] Researchers compared the therapeutic potential of induced pluripotent stem cells differentiation into MSCs generated from urinary epithelial cells with the available umbilical cord MSCs.

[Cell] Investigators characterized the proteogenomic landscape of lung squamous cell carcinoma (LSCC), providing a deeper exposition of LSCC biology with potential therapeutic implications.

[International Journal of Biochemistry & Cell Biology] An ovarian cancer cell line, PEO4, was reprogrammed into iPSCs using the classical four factors OCT4, SOX2, KLF4 and MYC (OSKM) using lentivirus transduction.

[International Journal of Biochemistry & Cell Biology] An ovarian cancer cell line, PEO4, was initially reprogrammed into induced pluripotent stem cells using the classical four factors OCT4, SOX2, KLF4 and MYC using lentivirus transduction.