T cells

[Cancer Immunology Research] Researchers used multicolor flow cytometry and immunohistochemistry to elucidate abundance and spatial distribution of these antigen-presenting B cells in blood and tumor samples of 238 cancer patients.

[EMBO Molecular Medicine] Scientists investigated this topic in an in vitro model using primary human T cells and in an immuno-nutritional intervention study enrolling healthy volunteers.

[Scientific Reports] The authors analyzed the profiling of immune cells in the peripheral blood of steroid-sensitive nephrotic syndrome patients and steroid-resistant nephrotic syndrome patients before and after standard steroid treatment to clarify the immunological mechanism of nephrotic syndrome patients.

[Science Advances] CD8+ T cells significantly infiltrated 12-dimethylbenz[a]anthracene (DMBA)-exposed breast cancers. CD8+ T cell depletion resulted in severe lung and liver metastasis in DMBA-treated polyoma middle tumor-antigen transgenic mice.

[Bioheng Biotech Co., Ltd.] Nanjing Bioheng Biotech Co., Ltd. announced UCAR T cell therapy product targeting CD7, received Orphan Drug Designation from the US FDA for the treatment of T-cell acute lymphoblastic leukemia (T-ALL).

[Frontiers in Immunology] Scientists investigated the effects of ionizing radiation on cancer-associated fibroblast (CAF)-mediated regulation of dendritic cells (DCs). CAFs were obtained from freshly operated lung cancer tissues, while DCs were procured from peripheral blood of healthy donors.