CD86+ Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-Cell Responses

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Researchers used multicolor flow cytometry and immunohistochemistry to elucidate abundance and spatial distribution of these antigen-presenting B cells in blood and tumor samples of 238 cancer patients.
[Cancer Immunology Research]
CD86+ antigen-presenting B cells are increased in cancer, localize in tertiary lymphoid structures, and induce specific T-cell responses | Cancer Immunology Research. (n.d.). Retrieved June 22, 2021, from https://cancerimmunolres.aacrjournals.org/content/early/2021/06/21/2326-6066.CIR-20-0949 Cite
Abstract