Ovarian clear cell carcinoma cell lines carrying wild-type p53 with low/high mouse double minute 2 homolog (MDM2) expression were investigated in a T-cell co-culture system evaluating T-cell-mediated tumor killing.
[Cell Death Discovery]
Sahin, I., Zhang, S., Navaraj, A., Zhou, L., Dizon, D., Safran, H., & El-Deiry, W. S. (2020). AMG-232 sensitizes high MDM2-expressing tumor cells to T-cell-mediated killing. Cell Death Discovery, 6(1), 1–7. https://doi.org/10.1038/s41420-020-0292-1 Cite
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