caspase-9

[Environmental Toxicology] Vemurafenib-resistant A375.S2 cells were established, and the functional mechanism of the epidermal growth factor receptor (EGFR), serine–threonine kinase, and the extracellular signal-regulated kinase signaling induced by curcumin was investigated in A375.S2/VR cells in vitro.

[Aging] Scientists explored the efficacy of anemoside B4 (AB4) in 5-Fluorouracil (FU)-based chemotherapy in colorectal cancer cells and the underlying molecular mechanisms. They indicated a significant synergistic activity of AB4 in 5-FU treated colorectal cancer cells

[Metallomics] Researchers found that maternal selenium (Se) deficiency decreased placental Se concentration and expressions of some antioxidant selenoproteins.

[Anti-Cancer Drugs] The results showed that atractylenolide III significantly inhibited the cell growth and induce cellular apoptosis in HCT-116 cells in a concentration dependence manner in vitro.

[Food & Function] The effects and pharmacological mechanisms of BRPS on the treatment of lung cancer were investigated both in vitro and in vivo.

[Bellicum Pharmaceuticals, Inc.] Bellicum Pharmaceuticals, Inc. and The University of Texas MD Anderson Cancer Center announced a global option and license agreement covering certain intellectual property and technology rights regarding Bellicum’s CaspaCIDe® safety switch and related technologies, and the use of rimiducid, an agent used to activate the safety switch.