Curcumin Suppresses Cell Proliferation and Triggers Apoptosis in Vemurafenib-Resistant Melanoma Cells by Downregulating the EGFR Signaling Pathway

Vemurafenib-resistant A375.S2 cells were established, and the functional mechanism of the epidermal growth factor receptor (EGFR), serine–threonine kinase, and the extracellular signal-regulated kinase signaling induced by curcumin was investigated in A375.S2/VR cells in vitro.