caspase-9

[Clinical Cancer Research] Scientists tested the safety and efficacy of chimeric antigen receptor T cell therapy in refractory/relapsed acute myeloid leukemia .

[Scientific Reports] Antibody–drug nanoparticles were engineered by synthesizing pure anti-cancer drug nanorods in the core of nanoparticles with a therapeutic monoclonal antibody, Trastuzumab on the surface of NRs for specific targeting and synergistic treatments of human epidermal growth factor receptor 2 positive breast cancer cells.

[Biological Research] Lotus leaf flavonoids (LLF) were applied to human lung cancer A549 cells and human small cell lung cancer cells H446 in vitro to verify the effect of LLF on apoptosis in these cells through the ROS/p38 MAPK pathway.

[Applied Microbiology and Biotechnology] The effects of lactonic sophorolipids and cell death inhibitors were measured by MTT test on HepG2 cells. Their morphology of the cells was observed under a microscope.

[PLoS One] Human CD24-/CD44+ breast cancer stem cells (BCSCs) were treated with andrographolide in vitro for 24 hours. The cytotoxic effect of andrographolide on BCSCs was compared to that on human mesenchymal stem cells.

[Scientific Reports] In order to evaluate the effect of chemically mimicked hypoxia on human PSCs cell survival, scientists analyzed changes in cell viability and several aspects of apoptosis triggered by CoCl2 and dimethyloxalylglycine.