Antibody–drug nanoparticles were engineered by synthesizing pure anti-cancer drug nanorods in the core of nanoparticles with a therapeutic monoclonal antibody, Trastuzumab on the surface of NRs for specific targeting and synergistic treatments of human epidermal growth factor receptor 2 positive breast cancer cells.
[Scientific Reports]
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Abedin, M. R., Powers, K., Aiardo, R., Barua, D., & Barua, S. (2021). Antibody–drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells. Scientific Reports, 11(1), 7347. https://doi.org/10.1038/s41598-021-86762-6 Cite