colorectal cancer

[iScience] Researchers addressed the contribution of posttranscriptional regulation, by the RNA-binding protein CPEB4, to intestinal immune homeostasis and its role in inflammatory bowel diseases and CRC development.

[Biochimie] The authors reviewed the recent progress of this signal transduction pathway in colorectal tumorigenesis.

[Oncogene] BEST4 is a member of the bestrophin protein family that plays a critical role in human intestinal epithelial cells. Scientists investigated the role and clinical significance of BEST4 in CRC.

[Cell Death & Disease] HERC3 was indicated to inhibit the migration, invasion and metastasis in vitro and in vivo through transwell assays, wound healing assays and vivo experiments.

[Signal Transduction and Targeted Therapy] Researchers found that IL-37 transgenic mice were highly susceptible to colitis-associated colorectal cancer and suffered from dramatically increased tumor burdens in colon.

[Signal Transduction and Targeted Therapy] Scientists found that IL-37 transgenic mice were highly susceptible to colitis-associated colorectal cancer and suffered from dramatically increased tumor burdens in colon.