Tag results:
cyclooxygenase-2
Cancer Stem Cell News
A Bioinspired Redox-Modulating Copper(ii)–Macrocyclic Complex Bearing Non-steroidal Anti-inflammatory Drugs with Anti-Cancer Stem Cell Activity
[Dalton Transactions] Investigators reported a biologically stable copper(II) complex based on the active site of Type I copper electron transport proteins.
Mesenchymal Cell News
Anti-Inflammatory Effects of Mesenchymal Stem Cell-Conditioned Media Inhibited Macrophages Activation In Vitro
[Scientific Reports] Scientists investigated the anti-inflammatory effects of MSCs on lipopolysaccharide-stimulated macrophages and the subsequent downregulation of their inflammatory mediators.
Pulmonary Cell News
Vitamin E Relieves Chronic Obstructive Pulmonary Disease by Inhibiting COX2-Mediated P-STAT3 Nuclear Translocation through the EGFR/MAPK Signaling Pathway
[Laboratory Investigation] Scientists explored the protective effect of vitamin E on chronic obstructive pulmonary disease and the underlying mechanisms.
Cancer Stem Cell News
Tumor-Initiating Stem Cell Shapes Its Microenvironment into an Immunosuppressive Barrier and Pro-Tumorigenic Niche
[Cell Reports] Using DNA-label retaining, single-cell RNA sequencing, and other approaches, researchers investigated intestinal adenoma in response to chemoradiotherapy, thus identifying therapy-resistant tumor-initiating stem cells.
Intestinal Cell News
Diclofenac Down-Regulates COX-2 Induced Expression of CD44 and ICAM-1 in Human HT29 Colorectal Cancer Cells
[Naunyn-Schmiedebergs Archives of Pharmacology] Scientists investigated the effect of diclofenac, a selective COX-2 inhibitor, on cell adhesion molecules and apoptosis in human colon adenocarcinoma cells. Levels of homing cell adhesion molecule, intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and epithelial cell adhesion molecule were evaluated in cancer cells overexpressing or not expressing COX-2.
Mammary Cell News
MicroRNA and Cyclooxygenase-2 in Breast Cancer
[Clinica Chimica Acta] Scientists present a comprehensive overview of the current literature concerning how miRNAs and cyclooxygenase-2 signaling interact in breast cancer progression.