epithelial cells

[eLife] Tumor-associated macrophages (TAMs) are abundant, and they are important mediators of disease progression and invasion. Scientists generated tumor-educated macrophages in vitro and performed detailed, multiomic characterization.

[Cell Death Discovery] Within LPS-treated MODE-K cells, METTL3 knockdown promoted cell viability, inhibited cell apoptosis, decreased apoptotic caspase3/9 cleavage, and decreased the levels of proinflammatory cytokines and inflammatory enzymes

[Current Biology] Investigators demonstrated that adult abdominal epidermal development was characterized by changes in the tissue microenvironment and a rapid exit from the cell cycle.

[Scientific Reports] Researchers found that miR-520a-5p bound the FZD9 3’UTR in lung cell lines and altered activity and expression of Frizzled 9 downstream targets.

[Clinical and Translational Oncology] The authors revealed ATG5-mediated autophagy was a key mechanism that controled the metastasis of prostate cancer by regulating p62 abundance and TWIST1 stabilization.

[Histology and Histopathology] Real-time quantitative PCR was used to detect the relative expression of fibroblast activation protein alpha mRNA in prostate cancer cell lines and human normal prostate epithelial cell line RWPE-1.