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epithelial cells

Membrane Vesicles of Lacticaseibacillus Rhamnosus JB-1 Contain Immunomodulatory Lipoteichoic Acid and Are Endocytosed by Intestinal Epithelial Cells

[Scientific Reports] Scientists demonstrated that membrane vesicles from Lacticaseibacillus rhamnosus JB-1 were endocytosed in a likely clathrin-dependent manner by both mouse and human intestinal epithelial cells (IECs) in vitro and by mouse IEC in vivo.

Cord Blood and Amniotic Membrane Extract Eye Drop Preparations Display Immune-Suppressive and Regenerative Properties

[Scientific Reports] Both placental-derived allogeneic preparations, cord blood platelet lysate and amniotic membrane extract eye drops, display regenerative and immunomodulatory capabilities.

Porcine Pancreatic Ductal Epithelial Cells Transformed with KRASG12D and SV40T Are Tumorigenic

[Scientific Reports] Primary pancreatic epithelial cells were isolated from pancreatic ducts of domestic pigs. A transformed cell line was generated from these primary cells with oncogenic KRAS and SV40T.

Weakening of Resistance Force by Cell-ECM Interactions Regulate Cell Migration Directionality and Pattern Formation

[Communications Biology] Investigators analyzed how the spatio-temporally remodeled ECM altered the resistance force exerted on cells so that the cells could expand their territory.

Epithelial Cell Plasticity Drives Endoderm Formation during Gastrulation

[Nature Cell Biology] Researchers used ESC and mouse embryo knock‐in reporter systems to combine time-resolved lineage labelling with high-resolution single-cell transcriptomics, which allowed them to resolve the morphogenetic programs that segregated the mesoderm from the endoderm germ layer.

Notch-IGF1 Signaling during Liver Regeneration Drives Biliary Epithelial Cell Expansion and Inhibits Hepatocyte Differentiation

[Science Signaling] Scientists used a temporally restricted model of hepatic repair in which large-scale hepatocyte injury and regeneration were initiated through the acute loss of Mdm2 in hepatocytes, resulting in the rapid, coordinated proliferation of biliary epithelial cells.

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