epithelial cells

[Digestive Diseases and Sciences] The authors provide novel insights into the role of chemical chaperone unfolded protein response modulators to modify endoplasmic reticulum (ER) stress levels in the pathogenesis of inflammatory bowel disease.

[Stem Cell Research & Therapy] Investigators focus on the proposed early and late therapeutic mechanisms of human amniotic epithelial cells and their exosomes to the injured organs.

[Nature Communications] Researchers demonstrated that an anticorisin monoclonal antibody ameliorated lung fibrosis by significantly inhibiting acute exacerbation in the human transforming growth factorβ1 model and acute lung injury in the bleomycin model.

[European Journal of Human Genetics] Investigators discovered an increased allelic expression pattern accompanied with overexpression of human leucocyte antigen (HLA)-B gene in SARS-CoV-2-infected human lung epithelial cells.

[Immunology & Cell Biology] Researchers presented a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection.

[Nature Biomedical Engineering] The authors showed that druggable biological targets and small-molecule regulators of intestinal stem cell differentiation could be identified via multiplexed phenotypic screening using thousands of miniaturized organoid models of intestinal stem cell differentiation into Paneth cells.