epithelial cells

[Mucosal Immunology] Scientists showed that epithelial Gpr35 plays a critical role in goblet cell function. In mice, cell-type-specific deletion of Gpr35 in epithelial cells but not in macrophages resulted in goblet cell depletion and dysbiosis, rendering these animals more susceptible to Citrobacter rodentium infection.

[European Journal of Histochemistry] Researchers showed that the level of miR-19a was significantly higher in clinical CRC tissue samples than in paracancerous tissue samples, and significantly higher in CRC cells lines HT29, SW480, and CaCO2 than in the normal human colon mucosal epithelial cell line NCM460.

[Scientific Reports] Researchers investigated the epithelial cell response to B. pertussis infection in primary human airway epithelium differentiated at air–liquid interface.

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.

[Communications Biology] The myoepithelial lineage of human breast is comprised of bipotent and multipotent progenitors in ducts and terminal duct lobular units. The authors assessed whether this heterogeneity impacted on oncogenic PIK3CA transformation.

[Cell Stem Cell] The authors purified human biliary epithelial cells from human livers that were not used for liver transplantation.