fibronectin

[Experimental Cell Research] Researchers explored the efficacy of the domains of secreted frizzled-related protein 4 (sFRP4) in inhibiting the key hallmarks of glioblastoma such as invasion, metastasis, and stemness.

[Scientific Reports] Scientists utilized cromolyn, a mast cell inhibitor with anti-inflammatory capabilities, and its fluorinated analogue F-cromolyn to study fibrosis-related protein regulation and secretion downstream of neuroinflammation and their ability to promote microglial phagocytosis and neurite outgrowth.

[Science Advances] Researchers aimed to identify the causal pathogenic mutation in an early-onset osteoarthritis family, followed by functional studies in human iPSCs in an in vitro organoid cartilage model.

[Polymer Journal] The authors used PNIPAAm-grafted substrates as a typical hydrophobic condensed polymer surface to investigate the effects of the lateral mobility of an adhesive ligand in the setting of lateral deformability of hydrophobic condensed polymer layers.

[Scientific Reports] Overexpression of miR-200c-3p resulted in a remarkable decrease in the expression of TLN1, which was associated with the suppression of integrin-mediated cell adhesion to fibronectin.

[Nature Communications] Researchers developed a material and culture system for modifying and measuring the degree to which cells retained cumulative effects of mechanosensing.