glioblastoma stem cells

[Cell Death & Disease] Scientists evaluated the functional activity and mechanism of TAK-243 in preclinical models of glioblastoma multiforme.

[Journal of Clinical Investigation] Researchers showed that glioblastoma stem cells, but not normal astrocytes, were sensitive to lysis by healthy allogeneic natural killer cells in vitro.

[Journal of Clinical Investigation] The authors showed that glioblastoma stem cells, but not normal astrocytes, were sensitive to lysis by healthy allogeneic natural killer cells in vitro.

[Cell Reports] Researchers explored the therapeutic potential of targeting mitochondrial translation and report the results of high-content screening with putative blockers of mitochondrial ribosomes.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers discovered correlated transcriptome-wide sex differences in gene expression, H3K27ac marks, large Brd4-bound enhancer usage, and Brd4 localization to Myc and p53 genomic binding sites. These sex-biased gene expression patterns were also evident in human glioblastoma stem cells.

[Signal Transduction and Targeted Therapy] Scientists summarize the basic characteristics, adaptive transition and implications of glioblastoma stem cells in glioblastoma therapy.