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Pulmonary Cell NewsResearchers explored the therapeutic potential of targeting mitochondrial translation and report the results of high-content screening with putative blockers of mitochondrial ribosomes.
[Cell Reports]
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Sighel, D., Notarangelo, M., Aibara, S., Re, A., Ricci, G., Guida, M., Soldano, A., Adami, V., Ambrosini, C., Broso, F., Rosatti, E. F., Longhi, S., Buccarelli, M., D’Alessandris, Q. G., Giannetti, S., Pacioni, S., Ricci-Vitiani, L., Rorbach, J., Pallini, R., … Quattrone, A. (2021). Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Reports, 35(4). https://doi.org/10.1016/j.celrep.2021.109024 Cite
