glioblastoma

[Developmental Cell] Scientists identified clones of patient-derived glioma propagating cells that were either highly proliferative or highly invasive and compared their cellular architecture, migratory, and biophysical properties.

[Cell Death & Disease] Scientists identified HOTAIRM1 as a candidate lncRNA whose up-regulation was significantly associated with shorter survival of glioblastoma patients, independent from IDH mutation and MGMT promoter methylation.

[Oncogene] The authors revisit biological characteristics and functions of infiltrating myeloid cells and discuss the recent advances in immunotherapies targeting infiltrating myeloid cells in glioblastoma .

[International Journal of Oncology] As the tumor microenvironment is typically acidic due to increased glycolysis and consequently leads to an increased production of lactic acid in tumor cells, the role of acid‑sensing ion channel 1a (ASIC1a), an acid sensor, was explored as a tumor suppressor in gliomagenesis and stemness.

[Nature Communications] Scientists identified SON as a master regulator that activates PTBP1-mediated oncogenic splicing while suppressing RBFOX2-mediated non-oncogenic neuronal splicing in glioblastoma multiforme.

[Scientific Reports] In search of novel putative therapeutic RNA targets researchers investigated the role of the oncogenic long noncoding RNA LINC00152 in A172 glioblastoma cells.