granulocytes

[Scientific Reports] Investigators found that elastolysis of elastic fibers and collagen accumulation contributed to vascular stiffening and arterial hypertension. Therefore, apelin expression could be a major element to preserve vascular homeostasis.

[Cell Death Discovery] Investigators isolated radiation-induced senescent tdTOMp16 positive MSCs, established their absence of cell division, then measured levels of irradiation-induced expression of biomarkers of senescence by RNA-seq analysis.

[Scientific Reports] Scientists utilized cromolyn, a mast cell inhibitor with anti-inflammatory capabilities, and its fluorinated analogue F-cromolyn to study fibrosis-related protein regulation and secretion downstream of neuroinflammation and their ability to promote microglial phagocytosis and neurite outgrowth.

[Cell Death Discovery] Scientists evaluated the effect of imipenem and ceftriaxone on neutrophil extracellular traps (NETs) formation in vitro and examined the role of reactive oxygen species.

[Molecular Pharmaceutics] Investigators used an in vitro peristaltic pump setup that mimiced pulsatile blood flow to determine if immune cells took up particles under constant fluidic flow.

[Journal of Experimental Medicine] Researchers observed that neutrophil DREAM repressed expression of A20, a negative regulator of NF-κB activity, and enhanced expression of pro-inflammatory molecules and phosphorylation of IκB kinase after TNF-α stimulation.