intestinal cells

[Journal of Cellular Physiology] Scientists characterized that Lactobacillus plantarum activated the farnesoid X receptor – fibroblast growth factor 15 signaling in intestinal epithelial cells and hence promoted DNA-damage repair.

[Bioengineered] Researchers clarified the role of hydroxysafflor yellow A in inhibiting colorectal cancer in vitro and the underlying mechanisms.

[Autoimmunity] Scientists reported the use of MSCs for the production and delivery of Gastrin, a peptide hormone that is produced by intestinal cells and fetal islets and can increase β-cell mass, to promote protection from type 1 diabetes.

[PLoS Genetics] Loss of mixed lineage leukemia 1 (MLL1) was accompanied by loss of intestinal stem cells and a differentiation bias towards the secretory lineage with increased numbers and enlargement of goblet cells.

[Frontiers in Immunology] Scientists summarize the changes brought about by the changes of commensal bacteria to the inflammation of the intestines and their mutual influence.

[Cell Metabolism] Scientists examined the microbial regulation of hexokinase 2 and its impact on inflammation using mice lacking hexokinase 2 in intestinal epithelial cells.