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intestinal epithelial cells

Effects of Mast Cells Induced by NSAIDs Impair Intestinal Epithelial Barrier Function In Vivo and In Vitro

[Inflammation] Investigators showed that mast cells activated PAR-2 in intestinal epithelial cells, downregulate the related proteins of cell tight junctions and cytoskeletal proteins, and increase the permeability of intestinal epithelial cells.

Effects of Mast Cells Induced by NSAIDs Impair Intestinal Epithelial Barrier Function In Vivo and In Vitro

[Inflammation] Intestinal epithelial cell line was applied with diclofenac sodium and its activity was detected by CCK-8.IEC-6 and RBL-2H3 were co-cultured to evaluate the permeability of intestinal epithelial cells by detecting the concentration of potassium ion and LDH.

The Intestinal Neuro-Immune Axis: Crosstalk between Neurons, Immune Cells, and Microbes

[Mucosal Immunology] The authors summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease.

The Intestinal Neuro-Immune Axis: Crosstalk between Neurons, Immune Cells, and Microbes

[Mucosal Immunology] Scientists summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease.

Infection of Porcine Small Intestinal Enteroids with Human and Pig Rotavirus A Strains Reveals Contrasting Roles for Histo-Blood Group Antigens and Terminal Sialic Acids

[PLoS Pathogens] Scientists established a porcine crypt-derived 3D intestinal enteroids culture system which contains all intestinal epithelial cells identified in vivo and represents a unique physiologically functional model to study rotavirus-glycan interactions in vitro.

Surfactant Protein A Reduces TLR4 and Inflammatory Cytokine mRNA Levels in Neonatal Mouse Ileum

[Scientific Reports] Surfactant protein A reduced expression of toll-like receptor 4 and proinflammatory cytokines in normal human intestinal epithelial cells.

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