leukocytes

[Scientific Reports] Scientists investigated the effect of extracellular vesicles derived from human umbilical cord-MSC on the clinical score and inflammatory/anti-inflammatory cytokines on the EAE mouse model.

[Scientific Reports] The authors investigated the immunosuppressive and immunomodulation abilities of Withaferin A and its effect on long-term islet allograft survival.

[Biomedicine & Pharmacotherapy] The authors examine the implications of lymphatic changes in IBD pathogenesis related to immune cells, gut microbiota, intestinal and mesenteric epithelial barrier integrity, and progression to colorectal cancer.

[Oncoimmunology] Researchers investigated the effects of CDK4/6i, abemaciclib and palbociclib, on the immunopeptidome at nontoxic levels in breast cancer cell lines using biochemical identification of HLA ligands followed by network analyses.

[Leukemia] The authors studied the impact of pretreatment with JAK1/2 inhibitor ruxolitinib on patient outcome after allogeneic hematopoietic stem cell transplantation.

[Nature Communications] Scientists reported, using the pathogenic model of antiretroviral therapy-treated, SIV-infected rhesus macaques that sequential interleukin-21 and interferon alpha therapy generated terminally differentiated blood natural killer cells with potent human leukocyte antigen-E-restricted activity in response to SIV envelope peptides.