liquid chromatography

[Rapid Communications in Mass Spectrometry] we developed and fully validated a liquid chromatography with tandem mass spectrometry (LC‐MS/MS) method for quantification of tigecycline in human lung epithelial cells and polymorphonuclear neutrophils.

[Expert Review of Proteomics] Scientists investigated the metabolic differences upon cisplatin treatment in lung cancer in vitro and in vivo.

[Med] Investigators explored human TNBC metabolism by isotope tracing with [1,2-13C]glucose, a tracer that differentiates glycolytic versus oxidative pentose phosphate pathway catabolism and reveals glucose-driven anabolism.

[Biomolecules] Investigators developed two hiPSC/hESC-specific glycan-recognizing mouse antibodies, R-10G and R-17F, using the Tic hiPSC line as an antigen. R-10G recognized a low-sulfate keratan sulfate, and R-17F recognized lacto-N-fucopentaose-1.

[Scientific Reports] Collection of an adequate number of PDAC cells is difficult due to the surrounding fibroblasts. The authors discovered novel biomarkers to predict chemosensitivity based on the collagen gel droplet-embedded drug sensitivity test results.

[Bioscience Reports] Researchers investigated intra-cellular lipid disturbances induced by adenomatous polyposis coli (APC) gene mutations in intestinal organoids using a reversed-phase ultra-high-performance liquid chromatography mass spectrometry-based lipid profiling method.