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Pulmonary Cell NewsInvestigators explored human TNBC metabolism by isotope tracing with [1,2-13C]glucose, a tracer that differentiates glycolytic versus oxidative pentose phosphate pathway catabolism and reveals glucose-driven anabolism.
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Ghergurovich, J. M., Lang, J. D., Levin, M. K., Briones, N., Facista, S. J., Mueller, C., Cowan, A. J., McBride, M. J., Rodriguez, E. S. R., Killian, A., Dao, T., Lamont, J., Barron, A., Su, X., Hendricks, W. P. D., Espina, V., Hoff, D. D. V., O’Shaughnessy, J., & Rabinowitz, J. D. (2021). Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer. Med, 0(0). https://doi.org/10.1016/j.medj.2021.03.009 Cite
