lymphocytes

[Cell Reports Medicine] Investigators demonstrated that AXL was a critical targetable driver of immune suppression in STK11/LKB1 mutant NSCLC.

[Journal of Translational Medicine] Researchers evaluated the functionality of mRNA-engineered dual-CAR NK-92 against tumor B cell lines and primary patient samples.

[Pediatric Research] The authors compared immune cell populations, inflammatory and anti-inflammatory cytokine and chemokine levels in the serum, and monocyte and T cell functional activity using umbilical cord samples from neonates with known opioid exposure during gestation and from control neonates without known exposure.

[Journal of Immunology] Scientists showed that PRMT5 drove allergic airway inflammation in a mouse model reproducing multiple aspects of human severe asthma.

[PDS Biotechnology Corporation] PDS Biotechnology Corporation announced that the National Cancer Institute (NCI) has achieved the intended enrollment objective of 30 patients in the checkpoint inhibitor refractory arm of the NCI-Led Phase II clinical trial evaluating PDS0101 in combination with two investigational immune-modulating agents in advanced HPV-associated cancers.

[BMC Infectious Diseases] A survey was conducted in men from an HIV cohort in Taizhou, China between 2016 and 2019. A face-to-face questionnaire interview was administered, and an anal-canal swab was collected for HPV genotyping.