lymphocytes

[Circulation] Investigators utilized mouse models of reperfused myocardial infarction, angiotensin II and phenylephrine infusion, and diphtheria toxin cardiomyocyte ablation to investigate C-C chemokine ligand 17.

[eLife] Scientists identified Zfp335 transcription factor as a new player in the regulatory network controlling thymocyte development in mice.

[Annual Reviews of Immunology] Scientists discussed known T cell–microbe interactions in the gut and placed them in the context of an algorithmic framework of recognition, context-dependent interpretation, and response circuits across multiple levels of microbial recognition resolution.

[LAVA Therapeutics] LAVA Therapeutics announced dosing of the first patient in the company’s Phase I/IIa clinical trial of LAVA-1207 in patients with metastatic CRPC.

[Clinical Cancer Research] Researchers characterized changes in the soft tissue sarcoma tumor immune microenvironment induced by standard neoadjuvant therapy with the goal of informing neoadjuvant immunotherapy trial design.

[Cell Death & Disease] The authors investigated the impact of apoptotic colorectal cancer cells on neutrophils and its consequence on other immune cells of the tumor microenvironment.