Tag results:
lymphoid cells
Immune Regulation News
Phosphoantigen-Stimulated γδ T Cells Suppress Natural Killer Cell-Responses to Missing-Self
[Cancer Immunology Research] Scientists studied the consequences of pAg-stimulated γδ T cell interactions with Natural Killer cells and CD8+ T cells, major innate and adaptive effectors, respectively.
Immune Regulation News
The Link between Circulating Follicular Helper T Cells and Autoimmunity
[Nature Reviews Immunology] The author discuss the increase in circulating Follicular helper T cells seen in autoimmune settings and explore potential explanations for this phenomenon.
Immunology of Infectious Disease News
Mild SARS-CoV-2 Infection in Rhesus Macaques Is Associated with Viral Control Prior to Antigen-Specific T Cell Responses in Tissues
[Science Immunology] The authors used rhesus macaques to model protective primary immune responses in tissues during mild COVID-19.
Pulmonary Cell News
Harpoon Therapeutics Granted Orphan Drug Designation for HPN328 for Treatment of Small Cell Lung Cancer
[Harpoon Therapeutics, Inc.] Harpoon Therapeutics, Inc. announced that the US FDA has granted Orphan Drug Designation for HPN328, a delta like ligand 3- targeting TriTAC®, for the treatment of SCLC.
Pulmonary Cell News
Bordetella pertussis-Infected Innate Immune Cells Drive the Anti-pertussis Response of Human Airway Epithelium
[Scientific Reports] Researchers investigated the epithelial cell response to B. pertussis infection in primary human airway epithelium differentiated at air–liquid interface.
ESC & iPSC News
Doxorubicin Induces Cardiotoxicity in a Pluripotent Stem Cell Model of Aggressive B Cell Lymphoma Cancer Patients
[Basic Research in Cardiology] Researchers established an in vitro iPSC model of anthracycline-induced cardiotoxicity (ACT) from patients with an aggressive form of B-cell lymphoma and examined whether doxorubicin-treated ACT-iPSC cardiomyocytes could recapitulate the clinical features exhibited by patients.