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lymphoid cells

Structural and Immunoendocrine Remodeling in Gut, Pancreas and Thymus in Weaning Rats Fed Powdered Milk Diets Rich in Maillard Reactants

[Scientific Reports] Researchers described that weaning rats fed diets rich in Maillard reaction products were affected in both their immune and endocrine systems.

TRAF6-Overexpressing Dendritic Cells Loaded with MUC1 Peptide Enhance Anti-Tumor Activity in B16-MUC1 Melanoma-Bearing Mice

[International Immunopharmacology] Tumor necrosis factor receptor-associated factor 6 (TRAF6)-overexpressing dendritic cells had increased expression of costimulatory molecules, major histocompatibility complex molecules and IL-12 expression.

Mitochondrial-Apoptotic Signaling Involvement in Remodeling during Myogenesis and Skeletal Muscle Atrophy

[Seminars in Cell & Developmental Biology] Scientists review the role of mitochondrial apoptotic signaling in skeletal muscle remodeling during myogenic differentiation and skeletal muscle pathological states, including aging, disuse, and muscular dystrophy.

Celyad Oncology Announces Voluntary Pause of CYAD-101-002 Phase Ib Trial

[Celyad Oncology] Celyad Oncology SA announced it has taken the decision to voluntarily pause the CYAD-101-002 Phase Ib trial due to reports of two fatalities that presented with similar pulmonary findings.

Tertiary Lymphoid Structures Generate and Propagate Anti-Tumor Antibody-Producing Plasma Cells in Renal Cell Cancer

[Immunity] Researchers used spatial transcriptomics to examine the nature of B cell responses within tertiary lymphoid structures in renal cell carcinoma.

TET2 Inactivation Restrains IL-10-Producing Regulatory B Cells to Enable Anti-Tumor Immunity in Hepatocellular Carcinoma

[Hepatology] TET2 activation in B cells triggered by oxidative stress from the hepatocellular carcinoma (HCC) microenvironment promoted IL-10 expression, while the adoptive transfer of Tet2-deficient B cells suppressed HCC progression.

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