macrophages

[Annals of Hematology] In this first clinical, phase I, dose-escalation and -expansion study, scientists evaluated CC-90002 in patients with relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.

[Tissue Engineering and Regenerative Medicine] Researchers reported a novel strategy to generate highly pure mouse bone marrow MSCs using liposomal clodronate.

[ACS Nano] The authors constructed a cocktail therapy to simultaneously regulate the osteoblast/osteoclast and M1/M2 macrophage balance.

[Nature Communications] Scientists described how heterocellular Oncostatin M (OSM) - Oncostatin M Receptor (OSMR) signaling reprograms fibroblasts, regulates tumor growth and metastasis.

[Nature Metabolism] Researchers identified the myokine/cytokine Meteorin-like (Metrnl) as a critical regulator of muscle regeneration.

[Molecular Therapy-Nucleic Acids] The authors explored the expression, role and mechanism of DNA damage regulated autophagy modulator 1 (DRAM1) in alcohol-related liver disease and revealed that ethanol-induced DRAM1 of hepatic cells could increase the pyruvate kinase M2 (PKM2)-enriched extracellular vesicles.