macrophages

[Cell Death Discovery] Researchers investigated the underlying mechanism of psychosocial stress in an inflammatory bowel disease mouse model pertaining to macrophage autophagy.

[Journal of Hepatology] Investigators undertook molecular and functional studies to interrogate the significance of the myeloid Ikaros–SIRT1 axis in the innate immune activation and to determine whether it served as a homeostatic sentinel in hepatic rejuvenation in mouse and human liver.

[Basic Research in Cardiology] A Total of 20 immune cell subtypes were identified among 46,040 cells. The function of immune cells in acute rejection were illustrated simultaneously.

[Proceedings of the National Academy of Sciences of the United States of America] Exposure of mouse CD4+ T cells to TNF and TGF-β generated Th17 cells that expressed low levels of IL-17 and high levels of inflammatory markers independently of IL-6 and STAT3.

[Nature Communications] The authors reported that the epigenetic regulator Ezh2 was essential for yolk sachematopoiesis but dispensable for subsequent aorta–gonad–mesonephros blood development.

[Experimental and Molecular Medicine] Scientists identified and functionally validated a lncRNA using human atherosclerotic plaques. Human aortic samples were obtained from patients who underwent aortic surgery, and tissues were classified according to atherosclerotic plaques.